PEER REVIEWED
Epigenetics and Immunosenescence Reversal: An Evidence-Based Longevity Paradigm
Karriem H. Ali, M.D. | (edited by Chris Gutch PhD.) | 2008
Humankind has long thought of aging as a gradual, time-dependent, deterioration in one‘s well-being and quality of life, with an increased incidence and severity of debilitating chronic diseases. However, current medical opinion argues for a fresh, and more enlightened perspective on aging. Indeed, until recently, clinical medicine has focused more upon mitigating the effects of aging rather than reversing the process itself. However, current developments in epigenetics and immunology mean that we are now ready to begin the greater challenge of halting or reversing the aging process. There is a vast body of scientific literature indicating that immune dysregulation — specifically of the innate immune system — may be the determinative factor for the seemingly inevitable functional decline of advancing age. This dysregulation is characterized by a continual, low—grade, over-reactive state of systemic immune processes, which promote, in whole or in part, the pathognomonic signs of many of the chronic diseases that we associate with aging (e.g., cardiovascular disease, Alzheimer’s disease, cancer, osteoarthritis, insulin—resistance, and diabetes).
Proven Results, Backed by Clinical Research
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Basophilic Response in Patients with Persistent Symptoms Attributed to Lyme Borreliosis Treated with Hydrolysed Arabinoxylan Rice Bran
Background and Objectives: MGN-3/Biobran (BRM4, Lentin Plus 1000 or Ribraxx) is a natural, rice bran-derived arabinoxylan immunoceutical that modulates the adaptive immune response to viral infections. In response to bacterial...
PEER REVIEWEDBasophilic Response in Patients with Persistent Symptoms Attributed to Lyme Borreliosis Treated with Hydrolysed Arabinoxylan Rice Bran
2025Background and Objectives: MGN-3/Biobran (BRM4, Lentin Plus 1000 or Ribraxx) is a natural, rice bran-derived arabinoxylan immunoceutical that modulates the adaptive immune response to viral infections. In response to bacterial...
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Biobran/MGN-3: A Promising Natural Strategy for Mitigating Kidney Damage and Immune Modulation During Etoposide Therapy
Although chemotherapy is one of the pillars in cancer treatment, its side effects have extremely harmful impacts on many of the body's organs. This study investigates the potential protective effect...
Biobran/MGN-3: A Promising Natural Strategy for Mitigating Kidney Damage and Immune Modulation During Etoposide Therapy
2025Although chemotherapy is one of the pillars in cancer treatment, its side effects have extremely harmful impacts on many of the body's organs. This study investigates the potential protective effect...
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Nanoparticle Enhanced. The Protective Effects of MGN-3 BioBran Against Ehrlich Ascites Carcinoma-Induced Toxicity in the Liver, Kidneys and Spleen of Mice
Background: Nanoparticle-enabled targeted drug delivery has proven effective in cancer treatment due to its ability to cross biological barriers, achieve therapeutic concentrations within tumors, and minimize adverse effects on surrounding...
Nanoparticle Enhanced. The Protective Effects of MGN-3 BioBran Against Ehrlich Ascites Carcinoma-Induced Toxicity in the Liver, Kidneys and Spleen of Mice
2025Background: Nanoparticle-enabled targeted drug delivery has proven effective in cancer treatment due to its ability to cross biological barriers, achieve therapeutic concentrations within tumors, and minimize adverse effects on surrounding...